ICD-10-CM Book 2024 Edition

Chapters  /  Chapter 18  /  R50-R69

General symptoms and signs (R50-R69)

R50 Fever of other and unknown origin
Excludes1 chills without fever (R68.83)
febrile convulsions (R56.0-)
fever of unknown origin during labor (O75.2)
fever of unknown origin in newborn (P81.9)
hypothermia due to illness (R68.0)
malignant hyperthermia due to anesthesia (T88.3)
puerperal pyrexia NOS (O86.4)
R50.2 Drug induced fever
UseAdditionalCode code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Excludes1 postvaccination (postimmunization) fever (R50.83)
R50.8 Other specified fever
R50.81 Fever presenting with conditions classified elsewhere
CodeFirst underlying condition when associated fever is present, such as with:
leukemia (C91-C95)
neutropenia (D70.-)
sickle-cell disease (D57.-)
nonPrimary Yes
R50.82 Postprocedural fever
Excludes1 postprocedural infection (T81.4-)
posttransfusion fever (R50.84)
postvaccination (postimmunization) fever (R50.83)
R50.83 Postvaccination fever
Postimmunization fever
R50.84 Febrile nonhemolytic transfusion reaction
FNHTR
Posttransfusion fever
R50.9 Fever, unspecified
Fever NOS
Fever of unknown origin [FUO]
Fever with chills
Fever with rigors
Hyperpyrexia NOS
Persistent fever
Pyrexia NOS
R51 Headache
Excludes2 atypical face pain (G50.1)
migraine and other headache syndromes (G43-G44)
trigeminal neuralgia (G50.0)
R51.0 Headache with orthostatic component, not elsewhere classified
Headache with positional component, not elsewhere classified
R51.9 Headache, unspecified
Facial pain NOS
R52 Pain, unspecified
Acute pain NOS
Generalized pain NOS
Pain NOS
Excludes1 acute and chronic pain, not elsewhere classified (G89.-)
localized pain, unspecified type - code to pain by site, such as:
abdomen pain (R10.-)
back pain (M54.9)
breast pain (N64.4)
chest pain (R07.1-R07.9)
ear pain (H92.0-)
eye pain (H57.1)
headache (R51.9)
joint pain (M25.5-)
limb pain (M79.6-)
lumbar region pain (M54.5-)
pelvic and perineal pain (R10.2)
shoulder pain (M25.51-)
spine pain (M54.-)
throat pain (R07.0)
tongue pain (K14.6)
tooth pain (K08.8)
renal colic (N23)
pain disorders exclusively related to psychological factors (F45.41)
R53 Malaise and fatigue
R53.0 Neoplastic (malignant) related fatigue
CodeFirst associated neoplasm
R53.1 Weakness
Asthenia NOS
Excludes1 age-related weakness (R54)
muscle weakness (generalized) (M62.81)
sarcopenia (M62.84)
senile asthenia (R54)
R53.2 Functional quadriplegia
Complete immobility due to severe physical disability or frailty
Excludes1 frailty NOS (R54)
hysterical paralysis (F44.4)
immobility syndrome (M62.3)
neurologic quadriplegia (G82.5-)
quadriplegia (G82.50)
R53.8 Other malaise and fatigue
Excludes1 combat exhaustion and fatigue (F43.0)
congenital debility (P96.9)
exhaustion and fatigue due to excessive exertion (T73.3)
exhaustion and fatigue due to exposure (T73.2)
exhaustion and fatigue due to heat (T67.-)
exhaustion and fatigue due to pregnancy (O26.8-)
exhaustion and fatigue due to recurrent depressive episode (F33)
exhaustion and fatigue due to senile debility (R54)
R53.81 Other malaise
Chronic debility
Debility NOS
General physical deterioration
Malaise NOS
Nervous debility
Excludes1 age-related physical debility (R54)
R53.82 Chronic fatigue, unspecified
Excludes1 chronic fatigue syndrome (G93.32)
myalgic encephalomyelitis (G93.32)
other post infection and related fatigue syndromes (G93.39)
postviral fatigue syndrome (G93.31)
R53.83 Other fatigue
Fatigue NOS
Lack of energy
Lethargy
Tiredness
Excludes2 exhaustion and fatigue due to depressive episode (F32.-)
R54 Age-related physical debility
Frailty
Old age
Senescence
Senile asthenia
Senile debility
Excludes1 age-related cognitive decline (R41.81)
sarcopenia (M62.84)
senile psychosis (F03)
senility NOS (R41.81)
age Adult: [15-124]
R55 Syncope and collapse
Blackout
Fainting
Vasovagal attack
Excludes1 cardiogenic shock (R57.0)
carotid sinus syncope (G90.01)
heat syncope (T67.1)
neurocirculatory asthenia (F45.8)
neurogenic orthostatic hypotension (G90.3)
orthostatic hypotension (I95.1)
postprocedural shock (T81.1-)
psychogenic syncope (F48.8)
shock NOS (R57.9)
shock complicating or following abortion or ectopic or molar pregnancy (O00-O07, O08.3)
shock complicating or following labor and delivery (O75.1)
Stokes-Adams attack (I45.9)
unconsciousness NOS (R40.2-)
R56 Convulsions, not elsewhere classified
Excludes1 dissociative convulsions and seizures (F44.5)
epileptic convulsions and seizures (G40.-)
newborn convulsions and seizures (P90)
R56.0 Febrile convulsions
R56.00 Simple febrile convulsions
Febrile convulsion NOS
Febrile seizure NOS
R56.01 Complex febrile convulsions
Atypical febrile seizure
Complex febrile seizure
Complicated febrile seizure
Excludes1 status epilepticus (G40.901)
R56.1 Post traumatic seizures
Excludes1 post traumatic epilepsy (G40.-)
R56.9 Unspecified convulsions
Convulsion disorder
Fit NOS
Recurrent convulsions
Seizure(s) (convulsive) NOS
R57 Shock, not elsewhere classified
Excludes1 anaphylactic shock NOS (T78.2)
anaphylactic reaction or shock due to adverse food reaction (T78.0-)
anaphylactic shock due to adverse effect of correct drug or medicament properly administered (T88.6)
anaphylactic shock due to serum (T80.5-)
electric shock (T75.4)
obstetric shock (O75.1)
postprocedural shock (T81.1-)
psychic shock (F43.0)
shock complicating or following ectopic or molar pregnancy (O00-O07, O08.3)
shock due to anesthesia (T88.2)
shock due to lightning (T75.01)
traumatic shock (T79.4)
toxic shock syndrome (A48.3)
R57.0 Cardiogenic shock
Excludes2 septic shock (R65.21)
R57.1 Hypovolemic shock
R57.8 Other shock
R57.9 Shock, unspecified
Failure of peripheral circulation NOS
R58 Hemorrhage, not elsewhere classified
Hemorrhage NOS
Excludes1 hemorrhage included with underlying conditions, such as:
acute duodenal ulcer with hemorrhage (K26.0)
acute gastritis with bleeding (K29.01)
ulcerative enterocolitis with rectal bleeding (K51.01)
R59 Enlarged lymph nodes
Includes swollen glands
Excludes1 lymphadenitis NOS (I88.9)
acute lymphadenitis (L04.-)
chronic lymphadenitis (I88.1)
mesenteric (acute) (chronic) lymphadenitis (I88.0)
R59.0 Localized enlarged lymph nodes
R59.1 Generalized enlarged lymph nodes
Lymphadenopathy NOS
R59.9 Enlarged lymph nodes, unspecified
R60 Edema, not elsewhere classified
Excludes1 angioneurotic edema (T78.3)
ascites (R18.-)
cerebral edema (G93.6)
cerebral edema due to birth injury (P11.0)
edema of larynx (J38.4)
edema of nasopharynx (J39.2)
edema of pharynx (J39.2)
gestational edema (O12.0-)
hereditary edema (Q82.0)
hydrops fetalis NOS (P83.2)
hydrothorax (J94.8)
newborn edema (P83.3)
pulmonary edema (J81.-)
R60.0 Localized edema
R60.1 Generalized edema
Excludes2 nutritional edema (E40-E46)
R60.9 Edema, unspecified
Fluid retention NOS
R61 Generalized hyperhidrosis
Excessive sweating
Night sweats
Secondary hyperhidrosis
CodeFirst , if applicable, menopausal and female climacteric states (N95.1)
Excludes1 focal (primary) (secondary) hyperhidrosis (L74.5-)
Frey's syndrome (L74.52)
localized (primary) (secondary) hyperhidrosis (L74.5-)
R62 Lack of expected normal physiological development in childhood and adults
Excludes1 delayed puberty (E30.0)
gonadal dysgenesis (Q99.1)
hypopituitarism (E23.0)
R62.0 Delayed milestone in childhood
Delayed attainment of expected physiological developmental stage
Late talker
Late walker
age Pediatric: [0-17]
R62.5 Other and unspecified lack of expected normal physiological development in childhood
Excludes1 HIV disease resulting in failure to thrive (B20)
physical retardation due to malnutrition (E45)
R62.50 Unspecified lack of expected normal physiological development in childhood
Infantilism NOS
R62.51 Failure to thrive (child)
Failure to gain weight
Excludes1 failure to thrive in child under 28 days old (P92.6)
age Pediatric: [0-17]
R62.52 Short stature (child)
Lack of growth
Physical retardation
Short stature NOS
Excludes1 short stature due to endocrine disorder (E34.3-)
R62.59 Other lack of expected normal physiological development in childhood
R62.7 Adult failure to thrive
age Adult: [15-124]
R63 Symptoms and signs concerning food and fluid intake
Excludes1 bulimia NOS (F50.2)
R63.0 Anorexia
Loss of appetite
Excludes1 anorexia nervosa (F50.0-)
loss of appetite of nonorganic origin (F50.89)
R63.1 Polydipsia
Excessive thirst
R63.2 Polyphagia
Excessive eating
Hyperalimentation NOS
R63.3 Feeding difficulties
Excludes2 eating disorders (F50.-)
feeding problems of newborn (P92.-)
infant feeding disorder of nonorganic origin (F98.2-)
R63.30 Feeding difficulties, unspecified
R63.31 Pediatric feeding disorder, acute
Pediatric feeding dysfunction, acute
CodeAlso , if applicable, associated conditions such as:
aspiration pneumonia (J69.0)
dysphagia (R13.1-)
gastro-esophageal reflux disease (K21.-)
malnutrition (E40-E46)
R63.32 Pediatric feeding disorder, chronic
Pediatric feeding dysfunction, chronic
CodeAlso , if applicable, associated conditions such as:
aspiration pneumonia (J69.0)
dysphagia (R13.1-)
gastro-esophageal reflux disease (K21.-)
malnutrition (E40-E46)
R63.39 Other feeding difficulties
Feeding problem (elderly) (infant) NOS
Picky eater
R63.4 Abnormal weight loss
R63.5 Abnormal weight gain
Excludes1 excessive weight gain in pregnancy (O26.0-)
obesity (E66.-)
R63.6 Underweight
UseAdditionalCode code to identify body mass index (BMI), if known (Z68.-)
Excludes1 abnormal weight loss (R63.4)
anorexia nervosa (F50.0-)
malnutrition (E40-E46)
R63.8 Other symptoms and signs concerning food and fluid intake
R64 Cachexia
Excludes1 abnormal weight loss (R63.4)
cachexia due to underlying condition (E88.A)
nutritional marasmus (E41)
R65 Symptoms and signs specifically associated with systemic inflammation and infection
R65.1 Systemic inflammatory response syndrome (SIRS) of non-infectious origin
CodeFirst underlying condition, such as:
heatstroke (T67.0-)
injury and trauma (S00-T88)
Excludes1 sepsis- code to infection
severe sepsis (R65.2)
R65.10 Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
Systemic inflammatory response syndrome (SIRS) NOS
nonPrimary Yes
R65.11 Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
UseAdditionalCode code to identify specific acute organ dysfunction, such as:
acute kidney failure (N17.-)
acute respiratory failure (J96.0-)
critical illness myopathy (G72.81)
critical illness polyneuropathy (G62.81)
disseminated intravascular coagulopathy [DIC] (D65)
encephalopathy (metabolic) (septic) (G93.41)
hepatic failure (K72.0-)
nonPrimary Yes
R65.2 Severe sepsis
Infection with associated acute organ dysfunction
Sepsis with acute organ dysfunction
Sepsis with multiple organ dysfunction
Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
CodeFirst underlying infection, such as:
infection following a procedure (T81.4-)
infections following infusion, transfusion and therapeutic injection (T80.2-)
puerperal sepsis (O85)
sepsis following complete or unspecified spontaneous abortion (O03.87)
sepsis following ectopic and molar pregnancy (O08.82)
sepsis following incomplete spontaneous abortion (O03.37)
sepsis following (induced) termination of pregnancy (O04.87)
sepsis NOS (A41.9)
UseAdditionalCode code to identify specific acute organ dysfunction, such as:
acute kidney failure (N17.-)
acute respiratory failure (J96.0-)
critical illness myopathy (G72.81)
critical illness polyneuropathy (G62.81)
disseminated intravascular coagulopathy [DIC] (D65)
encephalopathy (metabolic) (septic) (G93.41)
hepatic failure (K72.0-)
R65.20 Severe sepsis without septic shock
Severe sepsis NOS
nonPrimary Yes
R65.21 Severe sepsis with septic shock
nonPrimary Yes
R68 Other general symptoms and signs
R68.0 Hypothermia, not associated with low environmental temperature
Excludes1 hypothermia NOS (accidental) (T68)
hypothermia due to anesthesia (T88.51)
hypothermia due to low environmental temperature (T68)
newborn hypothermia (P80.-)
R68.1 Nonspecific symptoms peculiar to infancy
Excludes1 colic, infantile (R10.83)
neonatal cerebral irritability (P91.3)
teething syndrome (K00.7)
R68.11 Excessive crying of infant (baby)
Excludes1 excessive crying of child, adolescent, or adult (R45.83)
age Pediatric: [0-17]
R68.12 Fussy infant (baby)
Irritable infant
age Pediatric: [0-17]
R68.13 Apparent life threatening event in infant (ALTE)
Apparent life threatening event in newborn
Brief resolved unexplained event (BRUE)
CodeFirst confirmed diagnosis, if known
UseAdditionalCode code(s) for associated signs and symptoms if no confirmed diagnosis established, or if signs and symptoms are not associated routinely with confirmed diagnosis, or provide additional information for cause of ALTE
age Pediatric: [0-17]
R68.19 Other nonspecific symptoms peculiar to infancy
age Pediatric: [0-17]
R68.2 Dry mouth, unspecified
Excludes1 dry mouth due to dehydration (E86.0)
dry mouth due to Sjögren syndrome (M35.0-)
salivary gland hyposecretion (K11.7)
R68.3 Clubbing of fingers
Clubbing of nails
Excludes1 congenital clubfinger (Q68.1)
R68.8 Other general symptoms and signs
R68.81 Early satiety
R68.82 Decreased libido
Decreased sexual desire
age Adult: [15-124]
R68.83 Chills (without fever)
Chills NOS
Excludes1 chills with fever (R50.9)
R68.84 Jaw pain
Mandibular pain
Maxilla pain
Excludes1 temporomandibular joint arthralgia (M26.62-)
R68.89 Other general symptoms and signs
R69 Illness, unspecified
Unknown and unspecified cases of morbidity